Cheap flights from Cali to Panama City

From 374 USD — compare hundreds of airlines

We search 100+ flight sitesDirect flights~1h 22mReturn route: Panama City → Cali
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About this route

Compare flights from Cali to Panama City, a about 698 km route (around 1h 22m nonstop). We gather live prices from hundreds of airlines and agencies so you can find the cheapest and book on the official site, with no hidden fees. Direct flights are available. Airlines such as Copa Airlines operate this route.

Nonstop time
1h 22m
Distance
698 km
Stops
Nonstop
Airlines
1+

The airports on this route

Cali
Aeropuerto Internacional Alfonso Bonilla Aragón (Palmaseca)CLO

About 16 km from Cali, in Palmira

Getting around: Intercity buses, authorized taxis and apps

Downtown Cali is 20–30 min by highway; at night prefer an authorized taxi or app.

Panama City
Aeropuerto Internacional de TocumenPTY

About 25 km from downtown Panama City

Getting around: Metro + buses, authorized taxis and apps

Copa’s big connection hub: if you’re only connecting you rarely need to leave the airport.

How to get the best price

1The sticker price is real — but it moves fastLow fares last hours or days. If the number works, search it today; waiting rarely improves it.
2Buy 4–8 weeks aheadThat window usually holds the best fares; holidays call for even more margin.
3Flexibility = moneyShifting departure 2–3 days can move the fare 100+ US$. Tuesdays and Wednesdays tend to be cheap.

Airlines on this route

FAQ

What's the cheapest month to fly Cali to Panama City?

Prices vary by season; use the price calendar to find the cheapest month.

How long is the flight from Cali to Panama City?

A nonstop flight takes about 1h 22m and covers around 698 km. Connecting itineraries take longer.

Are there direct flights from Cali to Panama City?

Yes, this route has nonstop flights. Filter by "nonstop" to see them.

Which airlines fly from Cali to Panama City?

Copa Airlines operate this route, among others. Compare them all in the results.

When should I book Cali–Panama City flights?

As a rule of thumb, booking 3–8 weeks ahead and avoiding weekends and holidays tends to give the best prices. Use the calendar to spot the cheapest dates.

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Cali → Panama City · Live fares from 100+ sites — free, with no hidden fees.

Guides for your trip

Flights to this destination from other cities

Other routes from Cali

Return route: Panama City → Cali →Panama City · Travel guide →All flights from Cali →