Cheap flights from Guayaquil to Panama City
From 322 USD — compare hundreds of airlines
About this route
Compare flights from Guayaquil to Panama City, a about 1,239 km route (around 2h nonstop). We gather live prices from hundreds of airlines and agencies so you can find the cheapest and book on the official site, with no hidden fees. Direct flights are available. Airlines such as Copa Airlines, TAME operate this route.
Prices by date
Airlines on this route
FAQ
What's the cheapest month to fly Guayaquil to Panama City?
It's usually 2026-08, from 149 USD. Use the price calendar to compare other dates.
How long is the flight from Guayaquil to Panama City?
A nonstop flight takes about 2h and covers around 1,239 km. Connecting itineraries take longer.
Are there direct flights from Guayaquil to Panama City?
Yes, this route has nonstop flights. Filter by "nonstop" to see them.
Which airlines fly from Guayaquil to Panama City?
Copa Airlines, TAME operate this route, among others. Compare them all in the results.
When should I book Guayaquil–Panama City flights?
As a rule of thumb, booking 3–8 weeks ahead and avoiding weekends and holidays tends to give the best prices. Use the calendar to spot the cheapest dates.