Cheap flights from Panama City to Sao Paulo
from 276 US$

From 503 USD — compare hundreds of airlines

We search 100+ flight sitesDirect flights~6h 52mReturn route: Sao Paulo → Panama City

The cheapest month is usually 2026-09 · 276 US$

Live fares from 100+ sites — free, with no hidden fees.

About this route

Compare flights from Panama City to Sao Paulo, a about 5,090 km route (around 6h 52m nonstop). We gather live prices from hundreds of airlines and agencies so you can find the cheapest and book on the official site, with no hidden fees. Direct flights are available. Airlines such as Copa Airlines operate this route.

Nonstop time

6h 52m

Distance

5,090 km

Stops

Nonstop

Airlines

The airports on this route

Panama City

Aeropuerto Internacional de TocumenPTY

About 25 km from downtown Panama City

Getting around: Metro + buses, authorized taxis and apps

Copa’s big connection hub: if you’re only connecting you rarely need to leave the airport.

Sao Paulo

Aeropuerto Internacional de GuarulhosGRU

About 25 km from central São Paulo

Getting around: Train + metro (CPTM link), executive buses, taxis and apps

Brazil’s international gateway; São Paulo traffic is serious — the train link helps.

Sao Paulo

Aeropuerto de CongonhasCGH

In the city, about 8 km from downtown São Paulo

Getting around: Taxis, apps and city buses

Domestic and central: for flights within Brazil it often saves an hour of transfer.

When to buy and when to fly

Prices by date

Fares found by date — cheapest days in green.

See prices for my dates →

300 US$

10/09

288 US$

11/09

288 US$

12/09

288 US$

13/09

288 US$

14/09

288 US$

15/09

288 US$

16/09

288 US$

17/09

288 US$

18/09

288 US$

19/09

288 US$

20/09

288 US$

21/09

How to get the best price

1The sticker price is real — but it moves fastLow fares last hours or days. If the number works, search it today; waiting rarely improves it.

2Buy 4–8 weeks aheadThat window usually holds the best fares; holidays call for even more margin.

3Flexibility = moneyShifting departure 2–3 days can move the fare 100+ US$. Tuesdays and Wednesdays tend to be cheap.

Airlines on this route

Copa Airlines

FAQ

What's the cheapest month to fly Panama City to Sao Paulo?

It's usually 2026-09, from 276 USD. Use the price calendar to compare other dates.

How long is the flight from Panama City to Sao Paulo?

A nonstop flight takes about 6h 52m and covers around 5,090 km. Connecting itineraries take longer.

Are there direct flights from Panama City to Sao Paulo?

Yes, this route has nonstop flights. Filter by "nonstop" to see them.

Which airlines fly from Panama City to Sao Paulo?

Copa Airlines operate this route, among others. Compare them all in the results.

When should I book Panama City–Sao Paulo flights?

As a rule of thumb, booking 3–8 weeks ahead and avoiding weekends and holidays tends to give the best prices. Use the calendar to spot the cheapest dates.