Cheap flights from Saint Louis to San Diego
From 259 USD — compare hundreds of airlines
Direct flightsCheapest: 2026-07 · 172 US$
Prices by date
172 US$
01/07
172 US$
02/07
172 US$
03/07
Airlines on this route
FAQ
What's the cheapest month to fly Saint Louis to San Diego?
Usually 2026-07, from 172 USD.
Are there direct flights from Saint Louis to San Diego?
We show both direct and connecting options — filter to compare.