Cheap flights from Santiago to La Serena
from 27 US$

From 35 USD — compare hundreds of airlines

We search 100+ flight sitesDirect flights~0h 60mReturn route: La Serena → Santiago

The cheapest month is usually 2026-09 · 27 US$

Live fares from 100+ sites — free, with no hidden fees.

About this route

Compare flights from Santiago to La Serena, a about 394 km route (around 0h 60m nonstop). We gather live prices from hundreds of airlines and agencies so you can find the cheapest and book on the official site, with no hidden fees. Direct flights are available. Airlines such as Sky Airline, LATAM Chile operate this route.

Nonstop time

0h 60m

Distance

394 km

Stops

Nonstop

Airlines

The airports on this route

Santiago

Aeropuerto Internacional Arturo Merino BenítezSCL

About 20 km from downtown Santiago, in Pudahuel

Getting around: Official buses, shared transfers, authorized taxis and apps

When to buy and when to fly

Prices by date

Fares found by date — cheapest days in green.

See prices for my dates →

27 US$

09/09

How to get the best price

1The sticker price is real — but it moves fastLow fares last hours or days. If the number works, search it today; waiting rarely improves it.

2Buy 4–8 weeks aheadThat window usually holds the best fares; holidays call for even more margin.

3Flexibility = moneyShifting departure 2–3 days can move the fare 100+ US$. Tuesdays and Wednesdays tend to be cheap.

Airlines on this route

Sky Airline LATAM Chile

FAQ

What's the cheapest month to fly Santiago to La Serena?

It's usually 2026-09, from 27 USD. Use the price calendar to compare other dates.

How long is the flight from Santiago to La Serena?

A nonstop flight takes about 0h 60m and covers around 394 km. Connecting itineraries take longer.

Are there direct flights from Santiago to La Serena?

Yes, this route has nonstop flights. Filter by "nonstop" to see them.

Which airlines fly from Santiago to La Serena?

Sky Airline, LATAM Chile operate this route, among others. Compare them all in the results.

When should I book Santiago–La Serena flights?

As a rule of thumb, booking 3–8 weeks ahead and avoiding weekends and holidays tends to give the best prices. Use the calendar to spot the cheapest dates.