Cheap flights from Guayaquil to Santiago
from 263 US$

Compare hundreds of airlines Guayaquil–Santiago

We search 100+ flight sitesDirect flights~5hReturn route: Santiago → Guayaquil

The cheapest month is usually 2026-10 · 263 US$

Live fares from 100+ sites — free, with no hidden fees.

About this route

Compare flights from Guayaquil to Santiago, a about 3,611 km route (around 5h nonstop). We gather live prices from hundreds of airlines and agencies so you can find the cheapest and book on the official site, with no hidden fees. Direct flights are available. Airlines such as LATAM Chile operate this route.

Nonstop time

Distance

3,611 km

Stops

Nonstop

Airlines

The airports on this route

Guayaquil

Aeropuerto Internacional José Joaquín de OlmedoGYE

About 6 km from downtown Guayaquil

Getting around: Authorized taxis, city buses and apps

Santiago

Aeropuerto Internacional Arturo Merino BenítezSCL

About 20 km from downtown Santiago, in Pudahuel

Getting around: Official buses, shared transfers, authorized taxis and apps

When to buy and when to fly

Prices by date

Fares found by date — cheapest days in green.

See prices for my dates →

280 US$

01/10

273 US$

02/10

273 US$

03/10

273 US$

04/10

265 US$

05/10

263 US$

06/10

270 US$

07/10

268 US$

08/10

268 US$

09/10

268 US$

10/10

268 US$

11/10

268 US$

12/10

How to get the best price

1The sticker price is real — but it moves fastLow fares last hours or days. If the number works, search it today; waiting rarely improves it.

2Buy 4–8 weeks aheadThat window usually holds the best fares; holidays call for even more margin.

3Flexibility = moneyShifting departure 2–3 days can move the fare 100+ US$. Tuesdays and Wednesdays tend to be cheap.

Airlines on this route

LATAM Chile

FAQ

What's the cheapest month to fly Guayaquil to Santiago?

It's usually 2026-10, from 263 USD. Use the price calendar to compare other dates.

How long is the flight from Guayaquil to Santiago?

A nonstop flight takes about 5h and covers around 3,611 km. Connecting itineraries take longer.

Are there direct flights from Guayaquil to Santiago?

Yes, this route has nonstop flights. Filter by "nonstop" to see them.

Which airlines fly from Guayaquil to Santiago?

LATAM Chile operate this route, among others. Compare them all in the results.

When should I book Guayaquil–Santiago flights?

As a rule of thumb, booking 3–8 weeks ahead and avoiding weekends and holidays tends to give the best prices. Use the calendar to spot the cheapest dates.