Cheap flights from Guayaquil to Santiago
From 412 USD — compare hundreds of airlines
Live fares from 100+ sites — free, with no hidden fees.
About this route
Compare flights from Guayaquil to Santiago, a about 3,611 km route (around 5h nonstop). We gather live prices from hundreds of airlines and agencies so you can find the cheapest and book on the official site, with no hidden fees. Direct flights are available. Airlines such as LATAM Chile operate this route.
The airports on this route
About 6 km from downtown Guayaquil
Getting around: Authorized taxis, city buses and apps
About 20 km from downtown Santiago, in Pudahuel
Getting around: Official buses, shared transfers, authorized taxis and apps
How to get the best price
Airlines on this route
FAQ
What's the cheapest month to fly Guayaquil to Santiago?
Prices vary by season; use the price calendar to find the cheapest month.
How long is the flight from Guayaquil to Santiago?
A nonstop flight takes about 5h and covers around 3,611 km. Connecting itineraries take longer.
Are there direct flights from Guayaquil to Santiago?
Yes, this route has nonstop flights. Filter by "nonstop" to see them.
Which airlines fly from Guayaquil to Santiago?
LATAM Chile operate this route, among others. Compare them all in the results.
When should I book Guayaquil–Santiago flights?
As a rule of thumb, booking 3–8 weeks ahead and avoiding weekends and holidays tends to give the best prices. Use the calendar to spot the cheapest dates.
Compare your dates in seconds
Guayaquil → Santiago · Live fares from 100+ sites — free, with no hidden fees.