Cheap flights from Madrid to Panama City
from 490 US$

From 664 USD — compare hundreds of airlines

We search 100+ flight sitesDirect flights~10h 42mReturn route: Panama City → Madrid

The cheapest month is usually 2026-09 · 490 US$

Live fares from 100+ sites — free, with no hidden fees.

About this route

Compare flights from Madrid to Panama City, a about 8,162 km route (around 10h 42m nonstop). We gather live prices from hundreds of airlines and agencies so you can find the cheapest and book on the official site, with no hidden fees. Direct flights are available. Airlines such as Iberia operate this route.

Nonstop time

10h 42m

Distance

8,162 km

Stops

Nonstop

Airlines

The airports on this route

Madrid

Aeropuerto Adolfo Suárez Madrid-BarajasMAD

About 15 km from central Madrid

Getting around: Metro (line 8), Cercanías trains, express buses, taxis and apps

Taxis to the center run on an official flat rate — no meter surprises.

Panama City

Aeropuerto Internacional de TocumenPTY

About 25 km from downtown Panama City

Getting around: Metro + buses, authorized taxis and apps

Copa’s big connection hub: if you’re only connecting you rarely need to leave the airport.

When to buy and when to fly

Prices by date

Fares found by date — cheapest days in green.

See prices for my dates →

577 US$

01/09

593 US$

02/09

590 US$

03/09

590 US$

04/09

590 US$

05/09

590 US$

06/09

590 US$

07/09

588 US$

08/09

490 US$

09/09

577 US$

10/09

577 US$

11/09

577 US$

12/09

How to get the best price

1The sticker price is real — but it moves fastLow fares last hours or days. If the number works, search it today; waiting rarely improves it.

2Buy 4–8 weeks aheadThat window usually holds the best fares; holidays call for even more margin.

3Flexibility = moneyShifting departure 2–3 days can move the fare 100+ US$. Tuesdays and Wednesdays tend to be cheap.

Airlines on this route

Iberia

FAQ

What's the cheapest month to fly Madrid to Panama City?

It's usually 2026-09, from 490 USD. Use the price calendar to compare other dates.

How long is the flight from Madrid to Panama City?

A nonstop flight takes about 10h 42m and covers around 8,162 km. Connecting itineraries take longer.

Are there direct flights from Madrid to Panama City?

Yes, this route has nonstop flights. Filter by "nonstop" to see them.

Which airlines fly from Madrid to Panama City?

Iberia operate this route, among others. Compare them all in the results.

When should I book Madrid–Panama City flights?

As a rule of thumb, booking 3–8 weeks ahead and avoiding weekends and holidays tends to give the best prices. Use the calendar to spot the cheapest dates.