Cheap flights from Medellin to Panama City
from 183 US$

From 324 USD — compare hundreds of airlines

We search 100+ flight sitesDirect flights~1h 10mReturn route: Panama City → Medellin

The cheapest month is usually 2026-09 · 183 US$

Live fares from 100+ sites — free, with no hidden fees.

About this route

Compare flights from Medellin to Panama City, a about 532 km route (around 1h 10m nonstop). We gather live prices from hundreds of airlines and agencies so you can find the cheapest and book on the official site, with no hidden fees. Direct flights are available. Airlines such as Avianca, Copa Airlines, Avianca Costa Rica operate this route.

Nonstop time

1h 10m

Distance

532 km

Stops

Nonstop

Airlines

The airports on this route

Medellin

Aeropuerto Internacional José María Córdova (Rionegro)MDE

About 35 km from Medellín, in Rionegro

Getting around: Airport buses, authorized taxis and apps

This is the international airport; the ride down to the valley takes 45–60 min on a mountain road.

Medellin

Aeropuerto Olaya HerreraEOH

In the city, very close to central Medellín

Getting around: Taxis, city buses and apps

Regional flights on small aircraft only — central and very quick to use.

Panama City

Aeropuerto Internacional de TocumenPTY

About 25 km from downtown Panama City

Getting around: Metro + buses, authorized taxis and apps

Copa’s big connection hub: if you’re only connecting you rarely need to leave the airport.

When to buy and when to fly

Prices by date

Fares found by date — cheapest days in green.

See prices for my dates →

183 US$

10/09

How to get the best price

1The sticker price is real — but it moves fastLow fares last hours or days. If the number works, search it today; waiting rarely improves it.

2Buy 4–8 weeks aheadThat window usually holds the best fares; holidays call for even more margin.

3Flexibility = moneyShifting departure 2–3 days can move the fare 100+ US$. Tuesdays and Wednesdays tend to be cheap.

Airlines on this route

Avianca Copa Airlines Avianca Costa Rica

FAQ

What's the cheapest month to fly Medellin to Panama City?

It's usually 2026-09, from 183 USD. Use the price calendar to compare other dates.

How long is the flight from Medellin to Panama City?

A nonstop flight takes about 1h 10m and covers around 532 km. Connecting itineraries take longer.

Are there direct flights from Medellin to Panama City?

Yes, this route has nonstop flights. Filter by "nonstop" to see them.

Which airlines fly from Medellin to Panama City?

Avianca, Copa Airlines, Avianca Costa Rica operate this route, among others. Compare them all in the results.

When should I book Medellin–Panama City flights?

As a rule of thumb, booking 3–8 weeks ahead and avoiding weekends and holidays tends to give the best prices. Use the calendar to spot the cheapest dates.