Cheap flights from Panama City to Medellin
From 284 USD — compare hundreds of airlines
Live fares from 100+ sites — free, with no hidden fees.
About this route
Compare flights from Panama City to Medellin, a about 532 km route (around 1h 10m nonstop). We gather live prices from hundreds of airlines and agencies so you can find the cheapest and book on the official site, with no hidden fees. Direct flights are available. Airlines such as Avianca, Copa Airlines, Avianca Costa Rica operate this route.
The airports on this route
About 25 km from downtown Panama City
Getting around: Metro + buses, authorized taxis and apps
Copa’s big connection hub: if you’re only connecting you rarely need to leave the airport.
About 35 km from Medellín, in Rionegro
Getting around: Airport buses, authorized taxis and apps
This is the international airport; the ride down to the valley takes 45–60 min on a mountain road.
In the city, very close to central Medellín
Getting around: Taxis, city buses and apps
Regional flights on small aircraft only — central and very quick to use.
How to get the best price
Airlines on this route
FAQ
What's the cheapest month to fly Panama City to Medellin?
Prices vary by season; use the price calendar to find the cheapest month.
How long is the flight from Panama City to Medellin?
A nonstop flight takes about 1h 10m and covers around 532 km. Connecting itineraries take longer.
Are there direct flights from Panama City to Medellin?
Yes, this route has nonstop flights. Filter by "nonstop" to see them.
Which airlines fly from Panama City to Medellin?
Avianca, Copa Airlines, Avianca Costa Rica operate this route, among others. Compare them all in the results.
When should I book Panama City–Medellin flights?
As a rule of thumb, booking 3–8 weeks ahead and avoiding weekends and holidays tends to give the best prices. Use the calendar to spot the cheapest dates.
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Panama City → Medellin · Live fares from 100+ sites — free, with no hidden fees.