Cheap flights from Panama City to Guayaquil
From 449 USD — compare hundreds of airlines
About this route
Compare flights from Panama City to Guayaquil, a about 1,239 km route (around 2h nonstop). We gather live prices from hundreds of airlines and agencies so you can find the cheapest and book on the official site, with no hidden fees. Direct flights are available. Airlines such as Copa Airlines, TAME operate this route.
Prices by date
Airlines on this route
FAQ
What's the cheapest month to fly Panama City to Guayaquil?
It's usually 2026-08, from 187 USD. Use the price calendar to compare other dates.
How long is the flight from Panama City to Guayaquil?
A nonstop flight takes about 2h and covers around 1,239 km. Connecting itineraries take longer.
Are there direct flights from Panama City to Guayaquil?
Yes, this route has nonstop flights. Filter by "nonstop" to see them.
Which airlines fly from Panama City to Guayaquil?
Copa Airlines, TAME operate this route, among others. Compare them all in the results.
When should I book Panama City–Guayaquil flights?
As a rule of thumb, booking 3–8 weeks ahead and avoiding weekends and holidays tends to give the best prices. Use the calendar to spot the cheapest dates.