Cheap flights from Panama City to Santiago
From 636 USD — compare hundreds of airlines
Direct flightsCheapest: 2026-07 · 469 US$
Prices by date
469 US$
01/07
Airlines on this route
FAQ
What's the cheapest month to fly Panama City to Santiago?
Usually 2026-07, from 469 USD.
Are there direct flights from Panama City to Santiago?
We show both direct and connecting options — filter to compare.